MECHANISM OF HYDROGEN SULFIDE FORMATION FROM THIOSULFATE
نویسندگان
چکیده
منابع مشابه
Thiosulfate Mediates Cytoprotective Effects of Hydrogen Sulfide Against Neuronal Ischemia
BACKGROUND Hydrogen sulfide (H2S) exhibits protective effects in various disease models including cerebral ischemia-reperfusion (I/R) injury. Nonetheless, mechanisms and identity of molecules responsible for neuroprotective effects of H2S remain incompletely defined. In the current study, we observed that thiosulfate, an oxidation product of H2S, mediates protective effects of an H2S donor comp...
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Amyloid fibrils are large aggregates of misfolded proteins, which are often associated with various neurodegenerative diseases such as Alzheimer's, Parkinson's, Huntington's, and vascular dementia. The amount of hydrogen sulfide (H2S) is known to be significantly reduced in the brain tissue of people diagnosed with Alzheimer's disease relative to that of healthy individuals. These findings prom...
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The Shigella are generally regarded as organisms that fail to form hydrogen sulfide. In a recent report on a lead semisolid agar, Friewer and Shaughnessy (Am. J. Clin. Path., 8, 1) observed the formation of H2S by several strains of Shigella paradysenteriae (Flexner) and Shigelka sonnei in this medium and also by the lead acetate paper test, although no mention was made of this reaction by Shig...
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H2S derived from organic thiol metabolism has been proposed serve as an oxygen sensor in a variety of systems because of its susceptibility to oxidation and its ability to mimic hypoxic responses in numerous oxygen-sensing tissues. Thiosulfate, an intermediate in oxidative H2S metabolism can alternatively be reduced and regenerate H2S. We propose that this contributes to the H2S-mediated oxygen...
متن کاملBronchodilatory Effect of Hydrogen Sulfide in Rat
Objective(s) The aims of present study were to elucidate the effect of NaHS as a H2S donor on precontracted rat trachea smooth muscle, role of epithelium and nitric oxide in this action. Materials and Methods Tracheal rings from male adult Wistar rats were isolated and mounted in an organ bath containing Krebs–Henseleit solution under 1.5 g resting tension and contractions were recorded isom...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1959
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.77.5.630-637.1959